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Merck

ABE604

Anti-Bonzo Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, CD186, BONZO, STRL33, TYMSTR

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Bonzo Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

O00574

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CXCR6(10663)

Analysis Note

Evaluated by Western Blotting/Peptide Inhibition Assay in human spleen tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected Bonzo in 15 µg of human spleen tissue lysate.

Application

Detect CXCR6 using this rabbit polyclonal antibody, Anti-Bonzo Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 20 µg/mL from a representative lot detected Bonzo in human spleen tissue.

Biochem/physiol Actions

This antibody recognizes the N-terminus of Bonzo.

General description

G-protein coupled receptor bonzo (BONZO), also known as C-X-C chemokine receptor type 6 (CXCR6,CXC-R6,CXCR-6), CDw186 (CD186), G-protein coupled receptor STRL33 (STRL33), and TYMSTR, is a receptor for the C-X-C chemokine CXCL16 and is shown to be used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Certain G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b have been identified as HIV coreceptors. BONZO is expressed in lymphoid tissues and activated T cells.
~45 kDa observed. Uncharacterized bands may appear in some lysate(s).

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human Bonzo.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
ABE60404053252912269

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