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Merck

ABF13

Anti-Interleukin-10 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

technique(s)

western blot: suitable

NCBI accession no.

NP_034678

UniProt accession no.

P18893

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... IL10(3586)

General description

Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. IL-10 down regulates the expression of Th1 cytokines, major histocompatibility complex class II antigens, and costimulatory molecules on macrophages. It also enhaces B cell survival, proliferation, and antibody production. Knockout studies suggest that IL-10 is an immunoregulator in the intestinal tract.
~18 kDa observed.

Immunogen

GST-tagged recombinant protein corresponding to mouse Interleukin-10.

Application

Detect Interleukin-10 using this Anti-Interleukin-10 Antibody validated for use in WB.

Analysis Note

Control
Mouse Interleukin-10 recombinant protein
Evaluated by Western Blot in mouse Interleukin-10 recombinant protein.

Western Blot Analysis: 0.01 µg/mL of this antibody detected Interleukin-10 on 10 µg of mouse Interleukin-10 recombinant protein.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Exercise ameliorates high fat diet induced cardiac dysfunction by increasing interleukin 10.
Kesherwani, V; Chavali, V; Hackfort, BT; Tyagi, SC; Mishra, PK
Frontiers in Physiology null
Eva Latorre et al.
United European gastroenterology journal, 6(3), 446-453 (2018-05-19)
Inflammatory bowel diseases are consequence of an intestinal homeostasis breakdown in which innate immune dysregulation is implicated. Toll-like receptor (TLR)2 and TLR4 are immune recognition receptors expressed in the intestinal epithelium, the first physical-physiological barrier for microorganisms, to inform the

Global Trade Item Number

SKUGTIN
ABF1304053252296598

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