ABF213
Anti-BANF1 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
BANF1, Barrier to autointegration factor 1, BAF, breakpoint cluster region protein 1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse
technique(s)
immunofluorescence: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... BANF1(8815)
General description
Barrier-to-autointegration factor 1 (BANF1) is a member of the BAF family. BANF1 plays fundamental roles in gene expression, nuclear assembly, chromatin organization and gonad development. BANF1 may be involved in membrane recruitment and chromatin decondensation during nuclear assembly. BANF1 contains two non-specific dsDNA-binding sites which may promote DNA cross-bridging. BANF1 is known to be a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. It’s been shown that retroviruses utilize BANF1 for inhibiting self-destructing autointegration of retroviral DNA, and thereby promoting integration of viral DNA into the host chromosome. BANF1 is expressed widely, and more specifically in colon, brain, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen and testis.
~24 kDa observed. Uncharacterized bands may appear in some lysates.
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminus of human BANF1.
Application
Anti-BANF1 Antibody is a highly specific rabbit polyclonal antibody, that targets Barrier-to-autointegration factor 1 & has been tested in western blotting & Immunofluorescence.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected BANF1 in mouse kidney tissue.
Biochem/physiol Actions
This antibody recognizes the N-terminus of BANF1.
Analysis Note
Evaluated by Western Blotting in mouse kidney tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected BANF1 in 15 µg of mouse kidney tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected BANF1 in 15 µg of mouse kidney tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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