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Merck

ABN213

Anti-IL-12 alpha Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, NK cell stimulatory factor chain 1, NKSF1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-IL-12 alpha Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... IL12A(3592)

Analysis Note

Evaluated by Western Blotting in human lymph node tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.

Application

Immunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.
This IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.

Biochem/physiol Actions

This antibody recognizes the near C-terminus of IL-12 alpha

General description

Interleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.
~25 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABN1084

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
ABN21304053252859311

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