Key Documents

COA/COQ

ABN339

Anti-LRFN2 Antibody

Name: Anti-LRFN2 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Leucine-rich repeat and fibronectin type III domain-containing protein 2, synaptic adhesion-like molecule 1, LRFN2

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

species reactivity (predicted by homology)

human (immunogen homology)

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

Q9ULH4

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... LRFN2(57497)

General description

LRFN2 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bind to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

~100 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to human LRFN2.

Application

Detect the LRFN2 protein using this Anti-LRFN2 validated for use in WB & IHC.

Immunohistochemistry Analysis: 2.5 µg/mL of this antibody from a representative lot detected. LRFN2 in mouse brain tissue.

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

Biochem/physiol Actions

At least two isoforms of LRFN2 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat brain tissue lysate

Evaluated by Western Blot in rat brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected LRFN2 in 15 µg of rat brain tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)