Skip to Content
Merck

ABN481

Anti-Synaptopodin Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Synaptopodin, SYNPO

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(2)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Synaptopodin Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, human

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

Q8N3V7

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SYNPO(11346)

Analysis Note

Control
Rat brain tissue lysate
Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected SYNPO in 15 µg of rat brain tissue lysate.

Application

Detect Synaptopodin using this rabbit polyclonal antibody, Anti-Synaptopodin Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected SYNPO in human brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Synaptopodin (SYNPO) is an actin-associated protein that may play an important role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. It is expressed in the cerebral cortex. Mutations in SYNPO may be associated with nephrotic syndrome.
~95 kDa observed. Uniprot describes three isoforms at ~74 kDa, ~96 kDa, and ~97 kDa Uncharacterized bands may appear in some lysates.

Immunogen

Epitope: Near C-terminus.
KLH-conjugated linear peptide corresponding to a sequence near the C-terminus of human SYNPO.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified.
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hani Y Suleiman et al.
JCI insight, 2(16) (2017-08-18)
The architectural integrity of tissues requires complex interactions, both between cells and between cells and the extracellular matrix. Fundamental to cell and tissue homeostasis are the specific mechanical forces conveyed by the actomyosin cytoskeleton. Here we used super-resolution imaging methods
Yinghui Wang et al.
Renal failure, 46(2), 2381597-2381597 (2024-07-23)
Diabetic kidney disease (DKD) is one of the most common complications of diabetes. It is reported that mesenchymal stem cells (MSCs) derived exosomes (MSCs-Exo) may have great clinical application potential for the treatment of DKD, but the underlying mechanism has
Chunmei Xu et al.
Theranostics, 10(15), 6806-6824 (2020-06-20)
Diabetic nephropathy (DN) is mainly regarded as diabetic glomerulopathy, and its progression is tightly correlated with tubular epithelial lesions. However, the underlying molecular mechanisms linking tubular damage and glomerulopathy are poorly understood. Methods: We previously reported that the upregulation of

Global Trade Item Number

SKUGTIN
ABN48104053252870460

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service