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Key Documents

ABS454

Sigma-Aldrich

Anti-Aldh3A1 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Aldehyde dehydrogenase family 3 member A1, AldhIII, Aldehyde dehydrogenase, dimeric NADP-preferring, ALDHIII, Aldehyde dehydrogenase 3, Aldh3A1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

UniProt accession no.

P30838

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ALDH3A1(218)

General description

Aldehyde dehydrogenase family 3 member A1 (Aldh3A1) is a member of the aldehyde dehydrogenase (ALDH) superfamily. The ALDH family is a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. ALDHs are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. They are suggested to play a major role in the detoxification of alcohol-derived acetaldehyde. Aldh3A1 is shown to oxidize preferentially aromatic aldehyde substrates, and it may play a role in the oxidation of toxic aldehydes. Aldh3A1 is highly expressed in stomach, esophagus, lung and cornea. It represents between 5 to 50% of the water soluble protein fraction in mammalian corneas and it is implied to protect the cornea from UV-induced oxidative stress.
~48 kDa observed. Uncharacterized bands may appear in some lysate(s).

Immunogen

KLH-conjugated linear peptide corresponding to human Aldh3A1.

Application

Anti-Aldh3A1 Antibody is a highly specific rabbit polyclonal antibody, that targets Aldehyde Dehydrogenase & has been tested in western blotting.
Research Category
Signaling
Research Sub Category
Developmental Signaling

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human stomach tissue lysate
Evaluated by Western Blotting in human stomach tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected Aldh3A1 in 15 µg of human stomach tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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