Skip to Content
Merck

ABS491

Anti-ACOT7 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

acyl-CoA Thioesterase 7, acyl coenzyme A thioesterase 7, Cytosolic acyl coenzyme A thioester hydrolase, Brain acyl-CoA hydrolase, BACH, CTE-Iia, CTE-II, Long chain acyl-CoA thioester hydrolase

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat, human

technique(s)

western blot: suitable

NCBI accession no.

NP_009205

UniProt accession no.

O00154

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ACOT7(11332)

General description

ACOT7, also known as Acyl-CoA thioesterase 7, or Brain acyl-CoA hydrolase (BACH) or CTE-Iia/CTE-II, or Long chain acyl-CoA thioester hydrolase, and encoded by the gene ACOT7/BACH, is part of a family of enzymes called Acyl-CoA thioesterases which are enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. ACOT7 particularly plays an important physiological role in the brain because of the brain’s use of CoA metabolism. Additionally, ACOT7 may play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. ACOT7 is localized to the cytoplasm and mitochondria. ACOT7 is expressed in variety of cells and tissues. Isoform 4 is expressed exclusively in the brain.
~ 42 kDa observed

Immunogen

Linear peptide corresponding to human ACOT7.

Application

Detect Acyl-CoA thioesterase 7 using this rabbit polyclonal antibody, Anti-ACOT7 Antibody validated for use in western blotting.

Analysis Note

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ACOT7 in 10 µg of mouse brain tissue lysate.

Not finding the right product?  

Try our Product Selector Tool.

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service