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Key Documents

ABT270

Sigma-Aldrich

Anti-Pro-Biglycan Antibody

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

conjugate

unconjugated

Quality Level

antibody form

serum

clone

polyclonal

purified by

(unpurified)

species reactivity

human, mouse, rabbit

concentration

(Please refer to lot specific datasheet.)

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

target post-translational modification

unmodified

General description

41.65 kDa calculated
LPH-conjugated linear peptide corresponding to the signal and propeptide of human Pro-Biglycan.

Specificity

This antiserum recognizes only the biglycan preproprotein (368aa) and probiglycan (349aa), but not the mature biglycan (331aa) lacking the N-terminal signal and propeptide sequence. This polyclonal antiserum is also known by LF-104.

Application

Western Blotting Analysis: A representative lot detected Pro-Biglycan in BMP1 treated recombinant protein (von Marschall, Z., and Fisher, L.W. (2010). Biochem. Biophys. Res. Commun. 391(13):1374-1378).

Physical form

Rabbit polyclonal antibody serum with 0.05% sodium azide.

Preparation Note

Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Analysis Note

Evaluated by Immunohistochemistry in human and mouse skin tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Pro-Biglycan in human and mouse skin tissue.

Other Notes

Human, Mouse. Predicted to react with Monkey, Rat, Dog, Cat, and Horse based on 100% sequence homology.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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