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Merck

AQ127

Goat Anti-Mouse IgG Antibody, Fc

Chemicon®, from goat

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About This Item

eCl@ss:
32160702
UNSPSC Code:
12352203
NACRES:
NA.46
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IP, WB
Citations:
5
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biological source

goat

Quality Level

conjugate

unconjugated

antibody form

F(ab′)2 fragment of affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunoprecipitation (IP): suitable, western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

General description

Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Immunogen

purified mouse IgG Fc fragment

Application

Goat anti-Mouse IgG Antibody, Fc detects level of Mouse IgG & has been published & validated for use in ELISA, IP & WB.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies

Biochem/physiol Actions

Based on immunoelectrophoresis, the antibody reacts with the heavy chains on mouse IgG but not with the light chains on most mouse imnunoglobulins. No antibody was detected against mouse IgM, or against immunoglobulin serum proteins, but antibodies may cross-react with immunoglobulins from other species.

Physical form

Affinity Purified F(ab′)2 Antibody in liquid buffer of 0.01% Sodium Phosphate, 0.25 M NaCl, pH 7.6 containing no preservatives.

Preparation Note

Store at +2 to 8°C in undiluted aliquots for up to six months, sterile conditions. Do not freeze thaw.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sadia Samer et al.
JCI insight, 7(21) (2022-09-21)
TGF-β plays a critical role in maintaining immune cells in a resting state by inhibiting cell activation and proliferation. Resting HIV-1 target cells represent the main cellular reservoir after long-term antiretroviral therapy (ART). We hypothesized that releasing cells from TGF-β-driven
Helena de Puig et al.
Bioconjugate chemistry, 28(1), 230-238 (2017-01-18)
We investigated the effect of the protein corona on the function of nanoparticle (NP) antibody (Ab) conjugates in dipstick sandwich immunoassays. Ab specific for Zika virus nonstructural protein 1 (NS1) were conjugated to gold NPs, and another anti-NS1 Ab was
Helena de Puig et al.
Nano today, 47, 101669-101669 (2022-11-10)
Global public health infrastructure is unprepared for emerging pathogen epidemics, in part because diagnostic tests are not developed in advance. The recent Zika, Ebola, and SARS-CoV-2 virus epidemics are cases in point. We demonstrate here that multicolored gold nanoparticles, when



Global Trade Item Number

SKUGTIN
AQ12704053252402982