Key Documents

COA/COQ

FCMAB185AP

Milli-Mark^® Anti-CD19 -APC Antibody, clone HD37

Name: Milli-Mark<SUP>®</SUP> Anti-CD19 -APC Antibody, clone HD37
Brand: MM

clone HD37, Milli-Mark^®, from mouse

Synonym(s):

Differentiation antigen CD19

B-lymphocyte surface antigen B4

T-cell surface antigen Leu-12, B-lymphocyte antigen CD19

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

mouse

Quality Level

100

conjugate

Allophycocyanin conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

HD37, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark^®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

NP_001761.3

UniProt accession no.

P15391

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CD19(930)

General description

120 kDa (Pezzutto, 1987; Sato, 1997)

CD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).

Immunogen

Hairy cell leukemia cells

Application

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD19 -APC Antibody, clone HD37 is validated for use in FC for the detection of CD19 -APC.

Biochem/physiol Actions

Antibody recognizes Human CD19 antigen.

Physical form

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to APC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2

Preparation Note

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Analysis Note

Control
Human Lymphocytes

Evaluated by flow cytometry using Human Lymphocytes

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)