Milli-Mark^® Anti-CD56-PE Antibody, clone C5.9

Control
Human Lymphocytes

Evaluated by flow cytometry using human lymphocytes

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD56-PE Antibody, clone C5.9 is validated for use in FC for the detection of CD56.

Antibody recognizes Human CD56 antigen.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

140 kDa (Poggi, 2002; Lanier, 1989)

CD56 is a membrane glycoprotein which has multiple isoforms generated by alternative splicing from a single gene located on chromosome 11 (Costa, 1997). The core polypeptide is the 140 kDa isoform which can be variably glycosylated to produce mature species. The predominant isoform in NK and T cells is the transmembrane-anchored 140 kDa protein. In tissues, CD56 antigen is found in the cerebellum and cortex of the brain, and at neuromuscular junctions. This molecule is identical to the 140 kDa isoform of the neuronal cell adhesion molecule (N-CAM) (Poggi, 2002; Lanier, 1989). Additionally, CD56 is also present in certain large granular lymphocyte leukemias, small cell lung carcinomas, neural-derived tumors, myelomas, and myeloid leukemias (Poggi, 2002).

Human NK Cells

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Protein A purified

Purified Mouse monoclonal IgG2b conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany