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Merck

FCMAB289A4

Milli-Mark® Anti-PINK1-Alexa Fluor 488 Antibody, clone N4/49

clone N4/49, Milli-Mark®, from mouse

Synonym(s):

PTEN induced putative kinase 1, protein kinase BRPK, serine/threonine-protein kinase PINK1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Milli-Mark® Anti-PINK1-Alexa Fluor 488 Antibody, clone N4/49, clone N4/49, Milli-Mark®, from mouse

biological source

mouse

conjugate

ALEXA FLUOR™ 488

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

N4/49, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

NP_115785

UniProt accession no.

Q9BXM7

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PINK1(65018)

Related Categories

Analysis Note

Control
HEK293 cells
Evaluated by flow cytometry using HEK293 cells.

Application

Milli-Mark Anti-PINK1-Alexa Fluor 488 Antibody, clone N4/49 is an antibody against PINK1-Alexa Fluor 488 for use in FC.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Biochem/physiol Actions

Antibody recognizes human PINK1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.
Uniprot describes two isoforms exist with calculated Mw of 63 and 30 kDa

Immunogen

Recombinant protein corresponding to human PINK1.

Physical form

Protein G Purified
Purified mouse monoclonal IgG1k conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
FCMAB289A404053252294945

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