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Merck

FCMAB390F

Milli-Mark® Anti-pan Histone-FITC Antibody, clone H11-4

clone H11-4, Milli-Mark®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

FITC conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

H11-4, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... H3C1(8350)

Related Categories

General description

Antibody recognizes histones H1, H2A, H2B, H3, and H4. Calculated molecular weight for these histones range from 14 to 21 kDa
There are 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. The five major classes of histones are H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones. Histones feature a main globular domain and a long N terminal tail which are involved with the structure of the nucleosomes of the ′beads on a string′ structure. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation.

Application

This Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4 is validated for use in FC for the detection of pan Histone.

Biochem/physiol Actions

Due to the highly conserved nature of histones, this antibody is predicted to have wide species reactivity.

Analysis Note

Evaluated by flow cytometry using HeLa cells.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Related Content

New Products: Volume 3, 2012

New Products: Antibodies, Assays, Small Molecules, Inhibitors, and Proteins

Global Trade Item Number

SKUGTIN
FCMAB390F04053252420856

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