MAB10216
Anti-Flavivirus Group Antigen Antibody, clone D1-4G2-4-15
ascites fluid, clone D1-4G2-4-15, Chemicon®
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About This Item
eCl@ss:
32160702
UNSPSC Code:
12352203
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
D1-4G2-4-15, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable
isotype
IgG1, IgG2a
shipped in
dry ice
General description
The viruses of the family Flaviviridae are important arthropod-borne viruses in both human and veterinary medicine. They are transmitted by mosquito and ticks and usually are maintained in a transmission cycle in nature. They produce a broad spectrum of clinical responses in humans ranging from asymptomatic infection to fulminant encephalitis or haemorrhagic fever. Nearly 60 flaviviruses are known to exist but many are yet to be shown to cause disease in humans.
Immunogen
Dengue virus type 2 antigens
Application
Anti-Flavivirus Group Antigen Antibody, clone D1-4G2-4-15 detects level of Flavivirus Group Antigen & has been published & validated for use in IF.
Biochem/physiol Actions
Recognises flavivirus group specific antigens (Dengue virus, West Nile Virus, Japanese Encephalitis, Yellow Fever Virus, Zika virus etc). It binds to the fusion loop at the extremity of domain II of protein E.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Jacob T Beaver et al.
Human vaccines & immunotherapeutics, 16(9), 2092-2108 (2020-08-08)
A severe consequence of adult Zika virus (ZIKV) infection is Guillain-Barré Syndrome (GBS), where autoreactive antibodies attack peripheral and central nervous systems (CNS) resulting in neuro-ocular pathology and fatal complications. During virally induced GBS, autoimmune brain demyelination and macular degeneration
Natalie A Prow et al.
NPJ vaccines, 5, 44-44 (2020-06-19)
The Sementis Copenhagen Vector (SCV) is a new vaccinia virus-derived, multiplication-defective, vaccine technology assessed herein in non-human primates. Indian rhesus macaques (Macaca mulatta) were vaccinated with a multi-pathogen recombinant SCV vaccine encoding the structural polyproteins of both Zika virus (ZIKV)
Sheila Cabezas et al.
Journal of virology, 92(14) (2018-05-11)
Severe dengue virus (DENV) infection is associated with overactivity of the complement alternative pathway (AP) in patient studies. Here, the molecular changes in components of the AP during DENV infection in vitro were investigated. mRNA for factor H (FH), a