Skip to Content
Merck

Key Documents

MAB1312

Sigma-Aldrich

Mouse Anti-Human IgG4 Antibody, clone HP6023, Fc

clone HP6023, Chemicon®, from mouse

Synonym(s):

Anti-CD32, Anti-CD32B, Anti-FCG2, Anti-FCGR2, Anti-FCGR2C, Anti-FcGRIIB, Anti-FcRII-c, Anti-FcgammaRIIb, Anti-IGFR2

Sign Into View Organizational & Contract Pricing

Select a Size

All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

secondary antibodies

clone

HP6023, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
radioimmunoassay: suitable
western blot: suitable

isotype

IgG3

NCBI accession no.

NM_001002273.1
NM_001002274.1
NM_001002275.1
NM_004001.3

UniProt accession no.

P31994

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FCGR2B(2213)

Related Categories

Immunogen

Epitope: Fc fragment

Application

Mouse anti-Human IgG4 Antibody, clone HP6023, Fc is an antibody against Human IgG4 for use in ELISA, RIA & WB.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
This antibody employed as both a capture antibody and a detection antibody for human IgG subclass 4 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).

Final working dilutions must be determined by end user.

Biochem/physiol Actions

Human IgG4 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1- 0.08% human IgG subclass 2 - 0.01% human IgG subclass 3 - 0.04% human IgG subclass 4-100% Isoelectric Focusing: mean pI 7.7

Physical form

Format: Purified
Purified immunoglobulin. 0.02MPB+ 0.25M NaCl , Ph=7.6, 0.1% soduim azide.

Preparation Note

Maintain at 2 -8°C for up to one year in undiluted aliquots.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 411493-200UG

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

F Brière et al.
The Journal of experimental medicine, 179(2), 757-762 (1994-02-01)
During antigen-induced immune responses, human B cells switch isotype from immunoglobulin M (IgM)-IgD to IgG1-4, IgA1-2, or IgE. In the human, no cytokines have yet been demonstrated to act as switch factors for IgG1, IgG2, and IgG3. In this paper
Katherine A McLaughlin et al.
Journal of immunology (Baltimore, Md. : 1950), 183(6), 4067-4076 (2009-08-19)
Multiple sclerosis (MS) typically manifests in early to mid adulthood, but there is increasing recognition of pediatric-onset MS, aided by improvements in imaging techniques. The immunological mechanisms of disease are largely unexplored in pediatric-onset MS, in part because studies have

Global Trade Item Number

SKUGTIN
MAB131204053252668272

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service