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Key Documents

MAB1628

Sigma-Aldrich

Anti-Myosin Antibody, slow muscle, clone NOQ7.5.4D

clone NOQ7.5.4D, Chemicon®, from mouse

Synonym(s):

Anti-CMD1S, Anti-CMH1, Anti-MPD1, Anti-MYHCB, Anti-SPMD, Anti-SPMM

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

NOQ7.5.4D, monoclonal

species reactivity

rat, feline, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
radioimmunoassay: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_000257.2

UniProt accession no.

P12883

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MYH7B(57644)

Immunogen

Epitope: slow muscle
Myosin purified from myofibrils isolated from histochemically mixed human skeletal muscle.

Application

Anti-Myosin Antibody, slow muscle, clone NOQ7.5.4D is an antibody against Myosin for use in RIA, WB, IH.
Immunohistochemistry: frozen and formalin fixed sections.

Immunoblotting

RIA

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Slow myosin heavy chain. Clearly identifies Type 1 fibers. Within skeletal muscle MAB1628 is specific for slow myosin heavy chain in a wide variety of species. It reacts strongly with rat and feline slow myosin heavy chain. MAB1628 also identifies beta (slow) myosin heavy chain in heart ventricles.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Linda L Kusner et al.
Investigative ophthalmology & visual science, 51(1), 192-200 (2009-08-08)
Extraocular muscle (EOM) has a distinct skeletal muscle phenotype. The hypothesis for the study was that fibroblasts support the unique EOM phenotype and that perimysial fibroblasts derived from EOM have properties that distinguish them from fibroblasts derived from other skeletal
Lipid in skeletal muscle myotubes is associated to the donors' insulin sensitivity and physical activity phenotypes.
Bajpeyi, S; Myrland, CK; Covington, JD; Obanda, D; Cefalu, WT; Smith, SR; Rustan, AC; Ravussin, E
Obesity (Silver Spring, Md.) null
Camila Silva Foresto et al.
Journal of applied physiology (Bethesda, Md. : 1985), 121(3), 646-660 (2016-07-23)
Muscle loss occurs following injury and immobilization in adulthood and childhood, which impairs the rehabilitation process; however, far fewer studies have been conducted analyzing atrophic response in infants. This work investigated first the morphological and molecular mechanisms involved in immobilization-induced
Jenny Lund et al.
Scientific reports, 8(1), 9814-9814 (2018-07-01)
Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular processes are poorly described. This study
Jenny Lund et al.
PloS one, 12(4), e0175441-e0175441 (2017-04-14)
Physical activity has preventive as well as therapeutic benefits for overweight subjects. In this study we aimed to examine effects of in vivo exercise on in vitro metabolic adaptations by studying energy metabolism in cultured myotubes isolated from biopsies taken
View All Related Papers

Global Trade Item Number

SKUGTIN
MAB162804053252463778

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