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Merck

MAB1921

Anti-Laminin β1 Antibody, clone 4E10

ascites fluid, clone 4E10, Chemicon®

Synonym(s):

Laminin B1 Chain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-Laminin β1 Antibody, clone 4E10, ascites fluid, clone 4E10, Chemicon®

biological source

mouse

antibody form

ascites fluid

clone

4E10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NM_002291.1

UniProt accession no.

P07942

shipped in

dry ice

Application

Anti-Laminin β1 Antibody, clone 4E10 detects level of Laminin β1 & has been published & validated for use in ELISA, IH, IP & WB.
ELISA (50% maximal binding to human laminin): >1:1,600,000.

Immunofluorescence

Affinity chromatography

Immunoprecipitation

Immunoblotting

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Biochem/physiol Actions

Reacts with the B1 portion of intact laminin and blocks the neurite stimulating activity of laminin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Purified human laminin

Physical form

Liquid.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Abnormal expression of laminin beta 1 chain in skeletal muscle of adult-onset limb-girdle muscular dystrophy.
M Li, D W Dickson, A J Spiro, M Li, D W Dickson, A J Spiro
Archives of Neurology null
The osteogenic differentiation of human bone marrow MSCs on HUVEC-derived ECM and ?-TCP scaffold.
Kang, Y; Kim, S; Bishop, J; Khademhosseini, A; Yang, Y
Biomaterials null
Human laminin isolated in a nearly intact, biologically active form from placenta by limited proteolysis.
Wewer, U, et al.
The Journal of Biological Chemistry, 258, 12654-12660 (1983)
A sarcoglycan-dystroglycan complex anchors Dp116 and utrophin in the peripheral nervous system.
M Imamura, K Araishi, S Noguchi, E Ozawa
Human Molecular Genetics null
Increased laminin A expression in regenerating myofibers in neuromuscular disorders.
Mundegar, R R, et al.
Muscle and Nerve, 18, 992-999 (1995)
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