Key Documents
MAB1921
Anti-Laminin β1 Antibody, clone 4E10
ascites fluid, clone 4E10, Chemicon®
Synonym(s):
Laminin B1 Chain
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
antibody form
ascites fluid
clone
4E10, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Immunogen
Purified human laminin
Application
Anti-Laminin β1 Antibody, clone 4E10 detects level of Laminin β1 & has been published & validated for use in ELISA, IH, IP & WB.
ELISA (50% maximal binding to human laminin): >1:1,600,000.
Immunofluorescence
Affinity chromatography
Immunoprecipitation
Immunoblotting
Optimal working dilutions must be determined by end user.
Immunofluorescence
Affinity chromatography
Immunoprecipitation
Immunoblotting
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
Biochem/physiol Actions
Reacts with the B1 portion of intact laminin and blocks the neurite stimulating activity of laminin.
Physical form
Liquid.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Abnormal expression of laminin beta 1 chain in skeletal muscle of adult-onset limb-girdle muscular dystrophy.
M Li, D W Dickson, A J Spiro, M Li, D W Dickson, A J Spiro
Archives of Neurology null
Appearance and distribution of laminin A chain isoforms and integrin alpha 2, alpha 3, alpha 6, beta 1, and beta 4 subunits in the developing human small intestinal mucosa.
N Perreault, P H Vachon, J F Beaulieu, N Perreault, P H Vachon, J F Beaulieu
The Anatomical Record null
The osteogenic differentiation of human bone marrow MSCs on HUVEC-derived ECM and ?-TCP scaffold.
Kang, Y; Kim, S; Bishop, J; Khademhosseini, A; Yang, Y
Biomaterials null
Renate Kunert et al.
AIDS research and human retroviruses, 20(7), 755-762 (2004-08-17)
The human monoclonal antibody 4E10 has been generated previously by immortalization of peripheral blood cells from an HIV-1-infected individual. This antibody binds to the linear epitope NWFDIT on gp41 and exhibits exceptional neutralizing activity against a broad spectrum of primary
Human laminin isolated in a nearly intact, biologically active form from placenta by limited proteolysis.
Wewer, U, et al.
The Journal of Biological Chemistry, 258, 12654-12660 (1983)
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