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MAB2015

Anti-Aggrecan Antibody

CHEMICON®, mouse monoclonal, EFG-4

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
EFG-4, monoclonal
Species reactivity:
bovine, canine, pig, chicken, human, sheep, rabbit
Application:
ELISA, IHC, RIA, WB
Citations:
18
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Product Name

Anti-Cartilage Proteoglycan Antibody, adult, clone EFG-4, ascites fluid, clone EFG-4, Chemicon®

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

EFG-4, monoclonal

species reactivity

bovine, canine, pig, chicken, human, sheep, rabbit

should not react with

rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable, radioimmunoassay: suitable, western blot: suitable

isotype

IgG1κ

NCBI accession no.

NM_001135.2, NM_013227.2

UniProt accession no.

P16112

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ACAN(176)

Immunogen

Epitope: adult
Human adult cartilage proteoglycan.

Application

Anti-Cartilage Proteoglycan Antibody, adult, clone EFG-4 detects level of Cartilage Proteoglycan & has been published & validated for use in ELISA, RIA, WB, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins
Western blot: 1:1,00 - 1:200
Immunohistochemistry: 1:50 - 250
ELISA: 1:250 - 1: 2500
RIA: 1:20,000 - 1:40,000
Optimal working dilutions must be determined by the end user.I/

Biochem/physiol Actions

Recognizes the short peptides substituted with keratan sulfate side chains and within the core protein of proteoglycans in articular cartilages, chicken limb bud and cornea. Does not cross-react with human fetal cartilage proteoglycans.

Physical form

Ascites fluid

Preparation Note

Maintain at -20°C in aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adel Tekari et al.
Stem cell research & therapy, 7(1), 75-75 (2016-05-25)
The intervertebral disc (IVD) has limited self-healing potential and disc repair strategies require an appropriate cell source such as progenitor cells that could regenerate the damaged cells and tissues. The objective of this study was to identify nucleus pulposus-derived progenitor
Daniela A Frauchiger et al.
Tissue engineering. Part C, Methods, 25(10), 571-580 (2019-06-04)
Low back pain related to intervertebral disk (IVD) degeneration has a major socioeconomic impact on our aging society. Therefore, stem cell therapy to activate self-repair of the IVD remains an exciting treatment strategy. In this respect, tissue-specific progenitors may play
C Manferdini et al.
Journal of tissue engineering and regenerative medicine, 10(5), 374-391 (2013-03-16)
Osteochondral lesions require treatment to restore the biology and functionality of the joint. A novel nanostructured biomimetic gradient scaffold was developed to mimic the biochemical and biophysical properties of the different layers of native osteochondral structure. The present results show
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