MAB2120Z
Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free
clone ERIC-1, Chemicon®, from mouse
Synonym(s):
NeuralCellAdhesionMolecule, CD56, MAB2120
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
ERIC-1, monoclonal
species reactivity
human, pig
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1
suitability
not suitable for flow cytometry
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... NCAM1(4684)
General description
The previously assigned protein identifier P13592 has been merged into P13591. Full details can be found on the UniProt database.
Immunogen
Epitope: extracellular
Human Retinoblastoma tumor
Application
Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free is an antibody against NCAM for use in ELISA, WB, IH.
Immunohistology on frozen tissue sections acetone fixation only.
Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.
ELISA: 80 ng/mL
Does not work in flow cytometry.
Optimal working dilutions must be determined by end user.
Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.
ELISA: 80 ng/mL
Does not work in flow cytometry.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance
Neurofilament & Neuron Metabolism
Growth Cones & Axon Guidance
Neurofilament & Neuron Metabolism
Biochem/physiol Actions
Recognizes N-CAM expressed on developing and adult neuroectrodermal tissues in Humans. Neuroectodermal tumors also stain including Elioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumor are also highly reactive. Will react on Natural Killer cells. Recognizes 120, 140 and 180 kDa NCAM isoforms.
Physical form
Format: Purified
Liquid in PBS. Does not contain any preservatives
Preparation Note
Store at -20°C only. Avoid repeated freeze-thaw cycles.
Analysis Note
Control
Recommended positive control tissue: Neuroblastoma
Recommended positive control tissue: Neuroblastoma
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MAB2122
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Ambrose Y Jong et al.
Journal of extracellular vesicles, 6(1), 1294368-1294368 (2017-03-23)
Extracellular vesicles (EVs) have been the focus of great interest, as they appear to be involved in numerous important cellular processes. They deliver bioactive macromolecules such as proteins, lipids, and nucleic acids, allowing intercellular communication in multicellular organisms. EVs are
Stefanie M Hauck et al.
Molecular and cellular biology, 26(7), 2746-2757 (2006-03-16)
Apoptotic cell death of photoreceptors is the final event leading to blindness in the heterogeneous group of inherited retinal degenerations. GDNF (glial cell-line-derived neurotrophic factor) was found to rescue photoreceptor function and survival very effectively in an animal model of
Boel De Paepe et al.
Biomolecules, 10(4) (2020-04-03)
Myo-inositol exerts many cellular functions, which include osmo-protection, membrane functioning, and secondary messaging. Its Na+/myo-inositol co-transporter SLC5A3 is expressed in muscle tissue and further accumulates in myositis. In this study we focused on the peculiar subgroup of sporadic inclusion body
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB2120Z | 04053252667534 |
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