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Merck

MAB4023

Anti-c-erbB-3 Antibody, cytoplasmic domain, clone RTJ2

clone RTJ2, Chemicon®, from mouse

Synonym(s):

HER-3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-c-erbB-3 Antibody, cytoplasmic domain, clone RTJ2, clone RTJ2, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

RTJ2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ERBB3(2065)

Application

Detect c-erbB-3 using this Anti-c-erbB-3 Antibody, cytoplasmic domain, clone RTJ2 validated for use in ELISA, IH, IP & WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reactive with human c-erB-3. In normal tissues, c-erB-3 is found in non-dividing differentiated epithelial cells, neurons, and hepatocytes. In abnormal tissues, c-erB-3 is found in 80% of GI tract tumors and 20% of breast cancers.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Epitope: cytoplasmic domain
Synthetic peptide corresponding to a site on the cytoplasmic domain of the human c-erbB-3 oncoprotein

Physical form

Format: Purified
Liquid in PBS, containing azide as a preservative.

Preparation Note

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R Naidu et al.
British journal of cancer, 78(10), 1385-1390 (1998-11-21)
Expression of c-erbB3 protein was investigated in 104 primary breast carcinomas comprising nine comedo ductal carcinoma in situ (DCIS), 91 invasive ductal carcinomas and four invasive lobular carcinomas using two monoclonal antibodies, RTJ1 and RTJ2. Of the 91 invasive ductal

Related Content

Global Trade Item Number

SKUGTIN
MAB402304053252610837

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