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Merck

MAB4056

Anti-Angiotensin Converting Enzyme Antibody, clone i2H5

clone i2H5, Chemicon®, from mouse

Synonym(s):

ACE, CD143, DCP1, Peptidyl-dipeptidase A, Peptidase P

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About This Item

eCl@ss:
32160702
UNSPSC Code:
12352203

Product Name

Anti-Angiotensin Converting Enzyme Antibody, clone i2H5, clone i2H5, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

i2H5, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

suitability

not suitable for immunohistochemistry (Paraffin)

NCBI accession no.

NM_000789.2
NM_152830.1
NM_152831.1

UniProt accession no.

P12821

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... AGT(183)

Application

Anti-Angiotensin Converting Enzyme Antibody, clone i2H5 is an antibody against Angiotensin Converting Enzyme for use in ELISA, IP, IC, IH.
Immunohistochemistry (Danilov et al., 1987; Falkenhahn et al., 1995; Morrell et al., 1995) : 1:1,000 on fresh frozen or 4% paraformaldehyde fixed tissues. Does not work on paraffin embedded tissue.

Immunocytochemistry: 1:100. Reacts with endothelial cells, macrophages (activated) and THP1 cells (monocyte line).

Immunoprecipitation: 1:1,000

ELISA (Stevens et al., 1990): 1:1,000

Structure-function of ACE (Danilov et al., 1994)

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Hormones & Receptors

Biochem/physiol Actions

Angiotensin-converting enzyme [ACE] (N-terminal)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The previously assigned protein identifier P22966 has been merged into P12821. Full details can be found on the UniProt database.

Immunogen

Angiotensin-converting enzyme from human lung

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 100 mM borate buffer, pH 8.0 and 150 mM NaCl.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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