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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
STRO-1, monoclonal
Species reactivity:
human, primate
Application:
FACS, IF
Citations:
21
biological source
mouse
Quality Segment
antibody form
ascites fluid
antibody product type
primary antibodies
clone
STRO-1, monoclonal
species reactivity
human, primate
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunofluorescence: suitable
input
sample type mesenchymal stem cell(s)
isotype
IgM
shipped in
dry ice
target post-translational modification
unmodified
General description
STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.
Immunogen
CD34+ bone marrow cells
Application
Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.
Biochem/physiol Actions
Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.
Analysis Note
Control
Bone marrow cultures
Bone marrow cultures
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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