MAB443
Anti-Estrogen Receptor Antibody, clone AER304
ascites fluid, clone AER304, Chemicon®
Synonym(s):
ER
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
AER304, monoclonal
Species reactivity:
bovine, human, chicken, mouse
Application:
EMSA, IHC, IP, WB
Citations:
1
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
AER304, monoclonal
species reactivity
bovine, human, chicken, mouse
manufacturer/tradename
Chemicon®
technique(s)
electrophoretic mobility shift assay: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ESR1(2099)
Immunogen
Bovine estrogen receptor.
Epitope: a.a. 120-170
Application
Anti-Estrogen Receptor Antibody, clone AER304 is a Mouse Monoclonal Antibody for detection of Estrogen Receptor also known as ER & has been validated in EMSA, IP, WB & IHC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Western blot (human)
Immunoprecipitation (human)
Immunohistochemistry (mouse)
Optimal working dilutions must be determined by the end user.
Immunoprecipitation (human)
Immunohistochemistry (mouse)
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Estrogen receptor 67kD hormone binding subunit. Epitope localized between aa 120-170.
Physical form
Liquid
Preparation Note
Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.
Other Notes
Replaces: 04-227
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Shyam Nathan et al.
Breast cancer research and treatment, 166(3), 681-693 (2017-08-16)
We previously identified small molecules that fit into a BRCA1-binding pocket within estrogen receptor-alpha (ERα), mimic the ability of BRCA1 to inhibit ERα activity ("BRCA1-mimetics"), and overcome antiestrogen resistance. One such compound, the hydrochloride salt of NSC35446 ("NSC35446.HCl"), also inhibited