MAB4619
Anti-Bcl-XL Antibody, NT, clone 7D9
clone 7D9, Chemicon®, from mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
7D9, monoclonal
Application:
FACS, IF
Citations:
1
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
7D9, monoclonal
species reactivity
mouse
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunofluorescence: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... BCL2L1(598)
General description
Bcl-X consists of two isoforms, Bcl-XL (long), a 241 aa protein, and Bcl-XS (short), a 178 aa protein lacking a 63-aa domain that is well conserved among members of the Bcl-2 family. Bcl-XL represses cell death, while Bcl-XS favors cell death.Bcl-X has two isoforms, Bcl-XL (long) a 241 amino acid protein and Bcl-XS (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl-2 family. Bcl-XL represses cell death, while Bcl-XS favors cell death.
Immunogen
Synthetic peptide corresponding to amino acids 35-50 (TEAPEETEAERETPSA) of mouse Bcl-XL protein. This sequence is conserved at 15 of 16 residues in rat Bcl-XL.
Application
Immunofluorescence
Flow Cytometry
Optimal working dilutions must be determined by end user.
Flow Cytometry
Optimal working dilutions must be determined by end user.
This Anti-Bcl-XL Antibody, N-terminus, clone 7D9 is validated for use in FC, IF for the detection of Bcl-XL.
Biochem/physiol Actions
MAB4619 recognizes a protein of 27 kDa, identified as the Bcl-XL protein. Highly specific to Bcl-XL and shows no cross-reaction with Bcl-XS, Bcl-2alpha or Bax protein.
Physical form
Format: Purified
Immunoglobulin purified by protein A affinity chromatography. Liquid in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yiqing Li et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(2), E209-E218 (2017-01-05)
Retinal ganglion cells (RGCs), the projection neurons of the eye, cannot regenerate their axons once the optic nerve has been injured and soon begin to die. Whereas RGC death and regenerative failure are widely viewed as being cell-autonomous or influenced
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB4619 | 04053252502637 |