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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3B3, monoclonal
Application:
ICC, IHC (p), WB
Citations:
40
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
3B3, monoclonal
species reactivity
monkey, mouse, human
species reactivity (predicted by homology)
rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GRIA3(2892)
General description
AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.
~ 110 kDa
Immunogen
Fusion protein, N-terminus of GluR3
Application
Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P).
Immunohistochemistry: A previous lot of this antibody was used in IH.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.
Physical form
Format: Purified
Liquid in PBS. Contains no preservative.
Analysis Note
Control
Brain
Hippocampal tissue
Brain
Hippocampal tissue
Western Blot Analysis: A previous lot of this antibody was used in WB.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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