MAB5550

Anti-TorsinA Antibody

Name: Anti-TorsinA Antibody
Brand: MM

ascites fluid, Chemicon^®

Synonym(s):

Anti-AMC5, Anti-DYT1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-TorsinA Antibody, ascites fluid, Chemicon^®

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Chemicon^®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000113.2

UniProt accession no.

O14656

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... TOR1B(27348)

Analysis Note

Control
Positive Control: Human brain lysate, NGF treated PC12 cells.

Application

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Neurodegenerative Diseases

This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA.

Biochem/physiol Actions

TorsinA

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

37kDa

TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions.

Immunogen

Maltose binding protein fusion protein from human torsinA.

Physical form

Ascites

Liquid. Contaings no preservative

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Diminishing evidence for torsinA-positive neuronal inclusions in DYT1 dystonia.

Drew Pratt et al.

Acta neuropathologica communications, 4(1), 85-85 (2016-08-18)

Global Trade Item Number

SKU	GTIN
MAB5550	04053252359651

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