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Merck

MAB5674

Anti-Plectin Antibody, Clone 10F6

clone 10F6, Chemicon®, from mouse

Synonym(s):

Plackin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Plectin Antibody, Clone 10F6, clone 10F6, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

10F6, monoclonal

species reactivity

mouse, human, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

P30427

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ACTC1(70), ACTG1(71)

Analysis Note

Control
rat brain tissue lysate
Routinely tested on rat brain tissue lysate

Application

Detect Plectin using this Anti-Plectin Antibody, Clone 10F6 validated for use in WB, IH.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Neuronal & Glial Markers

Biochem/physiol Actions

Cat. # MAB5674 recognizes the cytoplasmic domain of Plectin.
Reactivity with other species has not been tested.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

300-500 kDa
The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other tissues. It also may regulate changes of lymphocyte cytoarchitecture during polarization and extravasation. This gene has alternative splicing of different 5′ exons to the first constant exon, which generates transcript variants that encode distinct isoforms

Immunogen

Gel-purified C5 Cell plectin

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified in PBS with 0.05% NaN3

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elena Ambrosini et al.
Glia, 41(3), 290-300 (2003-01-16)
Macrophage inflammatory protein-3alpha/CCL20 is a recently identified chemokine that binds to CCR6 and acts as a chemoattractant for memory/differentiated T-cells, B-cells, and immature dendritic cells. We have previously reported that CCL20 and CCR6 mRNAs are expressed in the CNS of
Sarah D Ackerman et al.
The Journal of experimental medicine, 215(3), 941-961 (2018-01-26)
Myelin is a multilamellar sheath generated by specialized glia called Schwann cells (SCs) in the peripheral nervous system (PNS), which serves to protect and insulate axons for rapid neuronal signaling. In zebrafish and rodent models, we identify GPR56/ADGRG1 as a

Global Trade Item Number

SKUGTIN
MAB567404053252397202

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