MAB858-2

Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G

Name: Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G
Brand: MM

clone 131-2G, from mouse

Synonym(s):

RSV

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G, clone 131-2G, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

131-2G, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable
immunofluorescence: suitable

isotype

IgG1κ

shipped in

wet ice

Quality Level

300

Application

Detect Respiratory Syncytial Virus using this Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G validated for use in ELISA & IF.

ELISA

Indirect Immunofluorescence (fresh frozen tissue sections)

Final working dilutions must be determined by end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

Biochem/physiol Actions

Glycoprotein, 89 kD. Recognizes both A and B strains.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.

Immunogen

Epitope: some type B strains

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Purified immunoglobulin. 1 mg/mL in 0.02M PB with 0.25M NaCl, pH=7.6 containing 0.1% sodium azide.

Preparation Note

Maintain at 2 to 8° C in aliquots for up to 12 months after date of receipt. Do not store in diluted format.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Human respiratory syncytial virus Memphis 37 grown in HEp-2 cells causes more severe disease in lambs than virus grown in Vero cells.

Rachel J Derscheid et al.

Viruses, 5(11), 2881-2897 (2013-11-29)

Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in infants and young children. A small percentage of these individuals develop severe and even fatal disease. To better understand the pathogenesis of severe disease and develop therapies unique

RSV pre-fusion F protein enhances the G protein antibody and anti-infectious responses.

Caixia Su et al.

NPJ vaccines, 7(1), 168-168 (2022-12-20)

Respiratory syncytial virus (RSV) infection in children is the most common viral respiratory infection and can cause severe lung damage or death. There is no licensed vaccine for preventing RSV infection. Previously we demonstrated that an RSV vaccine, BARS13, consisting

Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens.

Ana M Nuñez Castrejon et al.

Journal of virology, 96(7), e0220121-e0220121 (2022-03-11)

Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract disease of children, the elderly, and immunocompromised individuals. Currently, there are no FDA-approved RSV vaccines. The RSV G glycoprotein is used for viral attachment to host cells

Effects of Alterations to the CX3C Motif and Secreted Form of Human Respiratory Syncytial Virus (RSV) G Protein on Immune Responses to a Parainfluenza Virus Vector Expressing the RSV G Protein.

Bo Liang et al.

Journal of virology, 93(7) (2019-01-18)

Human respiratory syncytial virus (RSV) is a major pediatric respiratory pathogen. The attachment (G) and fusion (F) glycoproteins are major neutralization and protective antigens. RSV G is expressed as membrane-anchored (mG) and -secreted (sG) forms, both containing a central fractalkine-like

Exploratory Spatial Analysis of in vitro Respiratory Syncytial Virus Co-infections.

Simeonov, I; Gong, X; Kim, O; Poss, M; Chiaromonte, F; Fricks, J

Viruses null

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Global Trade Item Number

SKU	GTIN
MAB858-2	04053252504365

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