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Merck

MAB8754

Anti-Eastern Equine Encephalitis Antibody, Virus, clone 1A4B.6

clone 1A4B.6, Chemicon®, from mouse

Synonym(s):

EEE

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Eastern Equine Encephalitis Antibody, Virus, clone 1A4B.6, clone 1A4B.6, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

clone

1A4B.6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
inhibition assay: suitable (hemagglutination)

isotype

IgG2b

shipped in

wet ice

Quality Level

Application

Detect the Eastern Equine Encephalitis protein using this Anti-Eastern Equine Encephalitis, Virus, clone 1A4B.6 validated for use in ELISA, IF & Hemagglutination Inhibition.
ELISA

Indirect Immunofluorescence

Hemagglutination Inhibition

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

The MAb 1A4B-6 is an IgG2b antibody that reacts with an
E1 epitope shared by all alphaviruses. Encephalitis Virus: Strains Indentified:

Eastern Equine (EEE) N. American eastern equine (NJ/60);

S. American eastern equine (BeAn 5122)

Western Equine (WEE) Western equine (McMIllan); Highlands J (B-230);

Sindbis

Semliki Forest Semliki Forest

Venezuelan Equine (VEE) 1AB (TC-83 Vaccine, Trinidad Donkey, PTF-39);

1C (P676); 1D (3880); 1E ( Mena II);

1F(78V-3531); 2 (Fe3-7c); 3 (Mucambo);

4 (Pixuna); 5 (Cabassou)

Immunogen

Epitope: Virus

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS with 0.1% Sodium Azide.

Preparation Note

Maintain at 2 to 8°C for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marcel Kruchelski Tschá et al.
Virus evolution, 7(2), veab105-veab105 (2022-03-22)
Genomic and epidemiological surveillance are paramount for the discovery of new viruses with the potential to cross species barriers. Here, we present a new member of the genus Alphavirus found in Trichoprosopon and Wyeomia mosquitoes, tentatively named Pirahy virus (PIRAV).
JinZhu Ma et al.
Biotechnology journal, 16(8), e2100008-e2100008 (2021-06-28)
Western equine encephalitis virus (WEEV) causes lethal encephalitis in humans and equines, and it poses a serious public health threat in many countries. Therefore, the development of an efficient vaccine remains an important challenge for the prevention of WEEV infection.
Detection of eastern equine encephalitis virus in infected mosquitoes using a monoclonal antibody-based antigen-capture enzyme-linked immunosorbent assay
Brown, T M, et al
The American Journal of Tropical Medicine and Hygiene, 65, 208-213 (2001)
Efficient functional pseudotyping of oncoretroviral and lentiviral vectors by Venezuelan equine encephalitis virus envelope proteins
Kolokoltsov, Andrey A, et al
Journal of virology, 79, 756-763 (2005)
A J Johnson et al.
Journal of clinical microbiology, 38(5), 1827-1831 (2000-05-02)
Monoclonal antibody (MAb)-based capture enzyme-linked immunosorbent assays (ELISAs) for the detection of anti-arboviral immunoglobulin G (IgG ELISAs) were developed for a comprehensive array of medically important arboviruses from the Alphavirus, Flavivirus, and Bunyavirus genera. Tests were optimized and standardized so

Global Trade Item Number

SKUGTIN
MAB875404053252667558

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