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Merck

MAB8754

Anti-Eastern Equine Encephalitis Antibody, Virus, clone 1A4B.6

clone 1A4B.6, Chemicon®, from mouse

Synonym(s):

EEE

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
1A4B.6, monoclonal
Species reactivity:
human
Application:
ELISA, IF, inhibition assay
Citations:
20
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biological source

mouse

Quality Level

antibody form

purified immunoglobulin

clone

1A4B.6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunofluorescence: suitable, inhibition assay: suitable (hemagglutination)

isotype

IgG2b

shipped in

wet ice

Immunogen

Epitope: Virus

Application

Detect the Eastern Equine Encephalitis protein using this Anti-Eastern Equine Encephalitis, Virus, clone 1A4B.6 validated for use in ELISA, IF & Hemagglutination Inhibition.
ELISA

Indirect Immunofluorescence

Hemagglutination Inhibition

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

The MAb 1A4B-6 is an IgG2b antibody that reacts with an
E1 epitope shared by all alphaviruses. Encephalitis Virus: Strains Indentified:

Eastern Equine (EEE) N. American eastern equine (NJ/60);

S. American eastern equine (BeAn 5122)

Western Equine (WEE) Western equine (McMIllan); Highlands J (B-230);

Sindbis

Semliki Forest Semliki Forest

Venezuelan Equine (VEE) 1AB (TC-83 Vaccine, Trinidad Donkey, PTF-39);

1C (P676); 1D (3880); 1E ( Mena II);

1F(78V-3531); 2 (Fe3-7c); 3 (Mucambo);

4 (Pixuna); 5 (Cabassou)

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS with 0.1% Sodium Azide.

Preparation Note

Maintain at 2 to 8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marcel Kruchelski Tschá et al.
Virus evolution, 7(2), veab105-veab105 (2022-03-22)
Genomic and epidemiological surveillance are paramount for the discovery of new viruses with the potential to cross species barriers. Here, we present a new member of the genus Alphavirus found in Trichoprosopon and Wyeomia mosquitoes, tentatively named Pirahy virus (PIRAV).
Brandon J Beddingfield et al.
NPJ vaccines, 9(1), 47-47 (2024-02-28)
MVA-based monovalent eastern equine encephalitis virus (MVA-BN-EEEV) and multivalent western, eastern, and Venezuelan equine encephalitis virus (MVA-BN-WEV) vaccines were evaluated in the cynomolgus macaque aerosol model of EEEV infection. Macaques vaccinated with two doses of 5 × 108 infectious units
Detection of eastern equine encephalitis virus in infected mosquitoes using a monoclonal antibody-based antigen-capture enzyme-linked immunosorbent assay
Brown, T M, et al
The American Journal of Tropical Medicine and Hygiene, 65, 208-213 (2001)



Global Trade Item Number

SKUGTIN
MAB875404053252667558