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Merck

MAB88917

Anti-Vitronectin Antibody, clone 8E6(LJ8)

clone 8E6(LJ8), Chemicon®, from mouse

Synonym(s):

Serum spreading factor, S-protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Vitronectin Antibody, clone 8E6(LJ8), clone 8E6(LJ8), Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

8E6(LJ8), monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000638.3

UniProt accession no.

P04004

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... VTN(7448)

Application

Anti-Vitronectin Antibody, clone 8E6(LJ8) detects level of Vitronectin & has been published & validated for use in ELISA, WB, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins
Western blot: 5-20 μg/mL Stains cell-binding vitronectin.

Immunocytochemistry: 5-20 μg/mL

ELISA: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

The antibody reacts with human vitronectin, it does not react with human fibronectin (Hayman et al., 1983).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Purified human vitronectin from plasma.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-1108

Physical form

Format: Purified
Purified immunoglobulin. Liquid. Buffer = 0.02M Phosphate buffer, 0.25M NaCl, pH 7.6 with 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months.Avoid repeat freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Heli Tiensuu et al.
BMC medicine, 20(1), 141-141 (2022-04-29)
Preterm birth is defined as live birth before 37 completed weeks of pregnancy, and it is a major problem worldwide. The molecular mechanisms that lead to onset of spontaneous preterm birth are incompletely understood. Prediction and evaluation of the risk
Takahiro Tougan et al.
Scientific reports, 8(1), 5052-5052 (2018-03-24)
The malaria parasite Plasmodium falciparum proliferates in the blood stream where the host immune system is most active. To escape from host immunity, P. falciparum has developed a number of evasion mechanisms. Serine repeat antigen 5 (SERA5) is a blood stage antigen
Cuihong Jia et al.
Experimental neurology, 323, 113088-113088 (2019-11-05)
Vitronectin (VTN) is a blood protein produced mainly by the liver. We show that VTN leaks from the bloodstream into the injury site and neighboring subventricular zone (SVZ) following ischemic stroke (middle cerebral artery occlusion, MCAO) in adult mice. MCAO
Quynh T Phan et al.
PLoS pathogens, 18(7), e1010681-e1010681 (2022-07-08)
During hematogenously disseminated candidiasis, blood borne fungi must invade the endothelial cells that line the blood vessels to infect the deep tissues. Although Candida albicans, which forms hyphae, readily invades endothelial cells, other medically important species of Candida are poorly

Global Trade Item Number

SKUGTIN
MAB8891704053252315107

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