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Key Documents

MABC951

Sigma-Aldrich

Anti-CXCL16/SR-PSOX Antibody, clone 22-19-12

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

conjugate

unconjugated

Quality Level

antibody form

purified antibody

clone

22-19-12
monoclonal

purified by

using protein G

species reactivity

human, mouse

concentration

(Please refer to lot specific datasheet.)

technique(s)

flow cytometry: suitable
inhibition assay: suitable

isotype

IgG1κ

UniProt accession no.

target post-translational modification

unmodified

General description

24.405 kDa calculated.
Human IgG1 Fc-tagged recombinant human CXCL16/SR-PSOX extracellular fragment.

Application

Epitope: Chemokine domain.

Biochem/physiol Actions

Clone 22-19-12 neutralizes human CXCL16/SR-PSOX-mediated chemotactic and phagocytosis activities by targeting the exracellular chemokine domain (Shimaoka, T., et al. (2003). J. Immunol. 171(4):1647-1651).

Physical form

Purified mouse monoclonal IgG1κ antibody in PBS without preservatives.

Preparation Note

Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Analysis Note

Evaluated by Flow Cytometry in PMA-treated THP-1 human monocytes.

Flow Cytometry Analysis: 0.1 µg of this antibody detected CXCL16/SR-PSOX surface expression on PMA-treated THP-1 human monocytes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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