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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
13F9.1, monoclonal
Application:
IHC, WB
Citations:
-
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
13F9.1, monoclonal
species reactivity
human
species reactivity (predicted by homology)
mouse (immunogen homology)
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... S1PR5(53637)
General description
Sphingosine 1-phosphate receptor 5 (S1PR5 or S1P5), otherwise known as EDG8, is a G-protein coupled receptor which is activated by the lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi/0 alpha and G12 signaling pathways. S1P5 is highly abundant in the brain, particularly in the corpus callosum, but S1P5 has also been detected in the spleen, placenta, lung, aorta, and peripheral blood leukocytes. In the brain, it regulates the transformation of radial glial cells into astrocytes, and the migration of oligodendrocyte precursor cells during development.
~42 kDa observed
Immunogen
Recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 5 (S1P5).
Application
Detect Sphingosine 1-phosphate receptor 5 (S1P5) using this Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 validated for use in Western Blotting & IHC.
Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 5 in normal human cerebellum and normal placenta tissue.
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blot in Daudi cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Sphingosine 1-phosphate receptor 5 in 10 µg of Daudi cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Sphingosine 1-phosphate receptor 5 in 10 µg of Daudi cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| MABC98 | 04053252694257 |