MABF510
Anti-CD117 (c-Kit) Antibody (mouse), APC, clone ACK2
clone ACK2, 0.2 mg/mL, from rat
Synonym(s):
Mast/stem cell growth factor receptor Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
biological source
rat
conjugate
Allophycocyanin conjugate
antibody form
purified antibody
antibody product type
primary antibodies
clone
ACK2, monoclonal
species reactivity
mouse
packaging
antibody small pack of 25 μg
concentration
0.2 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG2bκ
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Kit(16590)
General description
This 145 kDa molecule is a member of the tyrosine kinase receptor family and is expressed by a majority of hematopoietic progenitor cells. The interaction of the mouse c-kit receptor and steel factor promotes proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells, and plays a role in signaling and activation of these cells.
Immunogen
Immunogen information for this antibody is proprietary information.
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
This rat monoclonal antibody Anti-CD117 (c-Kit) (mouse), APC, clone ACK2 validated for use in western blotting, IHC, ICC & Flow Cytometry for the detection of CD117 (c-Kit).
Physical form
Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
Size Exclusion Chromatography
Preparation Note
It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Analysis Note
The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.06 μg of this antibody detected CD117 (c-Kit) in one million C57Bl/6 bone marrow cells.
Flow Cytometry Analysis: 0.06 μg of this antibody detected CD117 (c-Kit) in one million C57Bl/6 bone marrow cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yao Chen et al.
Development (Cambridge, England), 143(9), 1502-1511 (2016-03-12)
Retinoic acid (RA) signaling is crucial for spermatogonial differentiation, which is a key step for spermatogenesis. We explored the mechanisms underlying spermatogonial differentiation by targeting expression of a dominant-negative mutant of retinoic acid receptor α (RARα) specifically to the germ