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Merck

MABN1117

Anti-Pannexin 1, clone EPR5556, Rabbit Monoclonal Antibody

clone EPR5556, from rabbit

Synonym(s):

Pannexin-1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-Pannexin 1, clone EPR5556, Rabbit Monoclonal Antibody, clone EPR5556, from rabbit

biological source

rabbit

antibody form

unpurified

antibody product type

primary antibodies

clone

EPR5556, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG

UniProt accession no.

Q96RD7

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PANX1(24145)

Analysis Note

Evaluated by Western Blotting in human fetal brain, SH-SY5Y, Caco-2, and NIH:OVACAR-3 lysates.

Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected Pannexin 1 in human fetal brain, SH-SY5Y, Caco-2, and NIH:OVACAR-3 lysates.

Application

Produced in collaboration with Epitomics
Research Category
Neuroscience
Research Sub Category
Signaling Neuroscience
This Anti-Pannexin 1, clone EPR5556, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of Pannexin 1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Pannexin 1 (PANX1) belongs to the innexin family. Innexin family members are the structural components of gap junctions. Pannexin 1 and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that Pannexin 1 alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
~48 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Immunogen

Synthetic peptide corresponding to human Pannexin 1.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Format: Unpurified
Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
Unpurified

Preparation Note

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

Certificates of Analysis (COA)

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