MABN118

Anti-Limk1 Antibody, clone 6C3.1| MABN118

Name: Anti-Limk1 Antibody, clone 6C3.1| MABN118
Brand: MM

clone 6C3.1, from mouse

Synonym(s):

LIM domain kinase 1, LIMK-1, Lim kinase 1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-Limk1 Antibody, clone 6C3.1| MABN118, clone 6C3.1, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6C3.1, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_002305

UniProt accession no.

P53667

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... LIMK1(3984)

Analysis Note

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Limk1 in 10 µg of human cortex tissue lysate.

Application

Detect Limk1 using this Anti-Limk1 Antibody, clone 6C3.1 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Limk1 in human thalamus and human cerebral cortex tissue.

General description

LIM Kinase 1 (LIMK1) is a protein kinase that plays an important role in cellular functions like cell motility and growth cone actin dynamics. LIMK1 contains one PDZ domain and two LIM domains which mediate protein to protein inteactions. It is widely expressed in the adult and fetal nervous system with the highest levels being found in the cerebral cortex. Mutations in LIMK1 have been associated with cardiovascular and musculo-skeletal abnormalities.

~72 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to human Limk1.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c