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Merck

MABN160

Anti-Syntenin-1 Antibody, clone 4F4.1

clone 4F4.1, 1 mg/mL, from mouse

Synonym(s):

Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4F4.1, monoclonal

species reactivity

human

concentration

1 mg/mL

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_001007068

UniProt accession no.

O00560

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SDCBP(6386)

General description

The syndecans are transmembrane proteoglycans that place structurally heterogeneous heparan sulfate chains at the cell surface and a highly conserved polypeptide in the cytoplasm. Syntenin (also known as SDCBP) is an approximately 33 kDa scaffolding protein that that binds to kainate receptor subunits via a PDZ interaction. There is extensive colocalization of syntenin and kainate receptors with particularly intense labeling for both proteins at growth cones. It is proposed that syntenin has a role both in controlling membrane organization and in determining the formation and maturation of synapses.
~32 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to human Syntenin-1. The immunogen has a 98% homology to Mouse and Rat.

Application

Detect Syntenin-1 using this Anti-Syntenin-1 Antibody, clone 4F4.1 validated for use in western blotting.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Syntenin-1 in 10 µg of HEK293 cell lysate.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Diantha Van De Vlekkert et al.
Bio-protocol, 10(7), e3576-e3576 (2021-03-05)
Exosomes are dynamic nanovesicles secreted by virtually all cells and are present in all biological fluids. Given their highly heterogeneous content exosomes have been implicated in many physiological and pathological processes that they exert by influencing cell-cell and cell-ECM communication.

Global Trade Item Number

SKUGTIN
MABN16004053252972638

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