MABN1834
Anti-phospho-Filamin-A (Ser2152) Antibody, clone PS2
clone PS2, from mouse
Synonym(s):
Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, phospho-Filamin-A (Ser2152)
About This Item
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
PS2, monoclonal
species reactivity
mouse, human
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
isotype
IgG2bκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer2152)
Gene Information
human ... FLNA (2316)
General description
Immunogen
Application
Neuroscience
Developmental Neuroscience
Western Blotting Analysis: A representative lot detected cellular FLN-A pSer2152 phosphorylation induction upon serum, forskolin, or EphB2-Fc addition to serum-starved CHP100 human neuroblastoma cells (Zhang, J. et al. (2013). J. Neurosci. 33(40):15735-15746).
Immunocytochemistry Analysis: A representative lot detected cellular FLN-A pSer2152 phosphorylation induction in neuronal progenitors from frontal cortex of E13.5–E14.5 mouse embryos, CHP100 human neuroblastoma cells, and A7, but not FLN-A-deficient M2, human melanoma cells upon forskolin addition (Zhang, J. et al. (2013). J. Neurosci. 33(40):15735-15746).
Immunofluorescence Analysis: A representative lot detected FLN-A pSer2152 immunoreactivity extended to the proliferative zone (PZ) surface at the periventricular heterotopia (PVH) congenital malformation site in the forebrain (FB) of E17.5 MEKK-/- mouse embryos in addition to the FLN-A pSer2152 immunoreactivity in the intermediate zone (IZ) and cortical plate (CP) seen in both wild-type and MEKK-knockout embryos by fluorescent immunohistochemistry (Sarkisian, M.R., et al. (2006). Neuron. 52(5):789-801).
Biochem/physiol Actions
Physical form
Preparation Note
Analysis Note
Western Blotting Analysis: A 1:125 dilution of this antibody detected Calyculin A-stimulated Filamin-A Ser2152 phosphorylation in mouse embryonic fibroblasts (MEFs).
Other Notes
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Global Trade Item Number
SKU | GTIN |
---|---|
MABN1834 | 04055977294347 |
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