MABN46

Anti-Chloride intracellular channel protein (CLIC1) Antibody, clone CPTC-CLIC1-1

Name: Anti-Chloride intracellular channel protein (CLIC1) Antibody, clone CPTC-CLIC1-1
Brand: MM

clone CPTC-CLIC1, from mouse

Synonym(s):

chloride intracellular channel 1, Chloride channel ABP, RNCC protein, Nuclear chloride ion channel 27, nuclear chloride ion channel protein, Regulatory nuclear chloride ion channel protein, chloride intracellular channel protein 1

Select a Size

All Photos(1)

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-Chloride intracellular channel protein (CLIC1) Antibody, clone CPTC-CLIC1-1, clone CPTC-CLIC1, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CPTC-CLIC1, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG2aκ

NCBI accession no.

NP_001279

UniProt accession no.

O00299

shipped in

wet ice

Quality Level

100

Gene Information

human ... CLIC1(1192)

Analysis Note

Control
Human liver tissue lysate

Evaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 0.25 µg/mL of this antibody detected CLIC1 on 10 µg of human liver tissue lysate.

Application

Anti-Chloride intracellular channel protein (CLIC1) Antibody, clone CPTC-CLIC1-1 detects level of Chloride intracellular channel protein (CLIC1) & has been published & validated for use in WB, IH.

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (http://antibodies.cancer.gov/antibodies/detail/CPTC-CLIC1-2)

Research Category
Neuroscience

Research Sub Category
Signaling Neuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Chloride intracellular channel protein 1 (CLIC1) is a part of the CLIC family of proteins. This family of proteins reconstitute in phospholipid vesicles and have been shown to have chloride channel action. CLIC1 may rotate between membrane-bound and soluble forms since it has been seen as a membrane protein and in the cytoplasm. When there is a lack of detergent, CLIC1 becomes membrane-bound and can act as an anion-selective channel. Recently, it has been shown that CLIC1 is required in angiogenesis and has a part in controlling integrin cell surface expression.

~27 kDa observed

Immunogen

Full length recombinant protein corresponding to human CLIC1.
Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Protein G

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Not finding the right product?

Try our Product Selector Tool.

Storage Class

10-13 - German Storage Class 10 to 13

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chloride intracellular channel 1 (CLIC1) contributes to modulation of cyclic AMP-activated whole-cell chloride currents in human bronchial epithelial cells.

Bo Liu et al.

Physiological reports, 6(2) (2018-01-26)

Chloride channels are known to play critical physiological roles in many cell types. Here, we describe the expression of anion channels using RNA Seq in primary cultures of human bronchial epithelial cells (hBECs). Chloride intracellular channel (CLIC) family members were

Serum-reduced media impacts on cell viability and protein expression in human lung epithelial cells.

Mahamud-Ur Rashid et al.

Journal of cellular physiology, 234(6), 7718-7724 (2018-12-06)

Serum starvation is a widely used condition in molecular biology experiments. Opti-MEM is a serum-reduced media used during transfection of genetic molecules into mammalian cells. However, the impact of such media on cell viability and protein synthesis is unknown. A549

Temporal proteomic analyses of human lung cells distinguish high pathogenicity influenza viruses and coronaviruses from low pathogenicity viruses.