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Merck

MABN484

Anti-FGF13 Protein Antibody, clone N91/27

clone N91/27, from mouse

Synonym(s):

Fibroblast growth factor 13, FGF-13Fibroblast growth factor homologous factor 2, FHF-2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-FGF13 Protein Antibody, clone N91/27, clone N91/27, from mouse

biological source

mouse

antibody product type

primary antibodies

clone

N91/27, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Quality Level

Gene Information

human ... FGF13(2258)

Analysis Note

Control
Human heart tissue lysate
Evaluated by Western Blotting in human heart tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF13 in 10 µg of human heart tissue lysate.

Application

Anti-FGF13 Protein Antibody, clone N91/27 is a highly specific mouse monoclonal antibody & that targets FGF & FGF Receptor & has been tested in western blotting.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
Western Blotting Analysis: A representative lot detected FGF13 in whole rat brain homogenate tissue lysate (Prof. J. Trimmer, University of California, Davis).

Biochem/physiol Actions

This antibody cross-reacts with FGF13a and FGF13b; Does not cross-react with FGF11, FGF12 or FGF14
expressed in heterologous cells (Prof. J. Trimmer, University of California, Davis).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Fibroblast growth factor 13 (FGF13) is also called Fibroblast growth factor homologous factor 2 (FHF-2) and is a member of the heparin-binding growth factors family. FGF13 is a microtubule-binding protein that directly binds tubulin leading to polymerization and stabilization of microtubules, and is critical to neuron polarization and migration in the cerebral cortex and the hippocampus.FGF13 is thought to regulate voltage-gated sodium channels transport and function, and may also play a role in MAPK signaling. FGF13 is ubiquitously expressed, but is predominantly found in the nervous system.
~ 28 kDa observed

Immunogen

Recombinant protein corresponding to human recombinant FGF13 protein.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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Storage Class

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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