Anti-FGF13 Protein Antibody, clone N91/27

Fibroblast growth factor 13 (FGF13) is also called Fibroblast growth factor homologous factor 2 (FHF-2) and is a member of the heparin-binding growth factors family. FGF13 is a microtubule-binding protein that directly binds tubulin leading to polymerization and stabilization of microtubules, and is critical to neuron polarization and migration in the cerebral cortex and the hippocampus.FGF13 is thought to regulate voltage-gated sodium channels transport and function, and may also play a role in MAPK signaling. FGF13 is ubiquitously expressed, but is predominantly found in the nervous system.

~ 28 kDa observed

Recombinant protein corresponding to human recombinant FGF13 protein.

Anti-FGF13 Protein Antibody, clone N91/27 is a highly specific mouse monoclonal antibody & that targets FGF & FGF Receptor & has been tested in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Western Blotting Analysis: A representative lot detected FGF13 in whole rat brain homogenate tissue lysate (Prof. J. Trimmer, University of California, Davis).

This antibody cross-reacts with FGF13a and FGF13b; Does not cross-react with FGF11, FGF12 or FGF14
expressed in heterologous cells (Prof. J. Trimmer, University of California, Davis).

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Human heart tissue lysate

Evaluated by Western Blotting in human heart tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF13 in 10 µg of human heart tissue lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.