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Merck

MABN824

Anti-α-Synuclein (SNCA) Antibody

mouse monoclonal, LB509

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Product Name

Anti-α-syn Antibody (amino acids 115-122), clone LB509,

antibody form

purified antibody

Quality Level

300

clone

LB509
monoclonal

purified by

using protein G

species reactivity

human, mouse

concentration

(Please refer to lot specific datasheet.)

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

UniProt accession no.

P37840

General description

Conjugated linear peptide corresponding to human α-syn (aa 115-122).
~15 kDa observed

Application

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected α-syn in human cerebral cortex tissue.
Western Blotting Analysis: A representative lot detected α-syn in PK-digested FL a-syn pffs (Guo, J.L., et al. (2013). Cell. 154:103-117).

Biochem/physiol Actions

This antibody detects a-Synuclein preformed fibrils that can cross seed tau fibrilliation.

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected α-syn in 10 µg of human brain tissue lysate.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
MABN82404055977144970

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