Skip to Content
Merck

MABN863

Anti-Cav1.2 alpha1c, clone 8F9.1 Antibody

clone 8F9.1, from mouse

Synonym(s):

Voltage-dependent L-type calcium channel subunit alpha-1C, Calcium channel, L type. alpha-1 polypeptide, isoform 1, cardiac muscle, Voltage-gated calcium channel subunit alpha Cav1.2

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(2)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Cav1.2 alpha1c, clone 8F9.1 Antibody, clone 8F9.1, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

8F9.1, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_000710

UniProt accession no.

Q13936

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CACNA1C(775)

Analysis Note

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 5.0 µg/mL of this antibody detected Cav1.2 alpha1c in 10 µg of human brain tissue lysate.

Application

Anti-Cav1.2 alpha1c, clone 8F9.1 | MABN863 is an antibody against Cav1.2 alpha1c for use in Western Blotting, Immunohistochemistry (Paraffin).
Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected Cav1.2 alpha1c in human cerebellum, human cerebral cortex, and human pancreas tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Many alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
~230 kDa observed. UniProt entry Q13936 describes 37 isoforms produced by alternative splicing.

Immunogen

Recombinant protein corresponding to human Cav1.2 alpha1c.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
MABN86304055977127027

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service