MABS31

Anti-Calcyclin Antibody, clone CPTC-Calcyclin-2

Name: Anti-Calcyclin Antibody, clone CPTC-Calcyclin-2
Brand: MM

clone CPTC-Calcyclin-2, from mouse

Synonym(s):

S100 calcium binding protein A6, S100 calcium binding protein A6 (calcyclin), protein S100-A6, calcyclin, S100 calcium-binding protein A6 (calcyclin), Growth factor-inducible protein 2A9, Calcyclin, Prolactin receptor-associated protein, S100 calcium-bin

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CPTC-Calcyclin-2, monoclonal

species reactivity

human

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG2aκ

NCBI accession no.

NP_055439

UniProt accession no.

P06703

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... S100A6(6277)

General description

Calcyclin, also known as S100A6, is a calcium binding protein that is highly expressed in fibroblasts and epithelial cells. Inhibition of calcyclin by p53 is part of the mechanism to control cell proliferation. Calcyclin is associated with cancer and metastasis and plays a role in cell cycle regulation.

~10 kDa observed

Immunogen

Full length recombinant protein corresponding to human Calcyclin.

Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program.

Application

Anti-Calcyclin Antibody, clone CPTC-Calcyclin-2 detects level of Calcyclin & has been published & validated for use in WB, ELISA, IH.

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Tara Hitke, Developmental Studies Hybridoma Bank, University of Iowa.)

Research Category
Signaling

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

Physical form

Format: Purified

Protein G

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human lung tissue lysate

Evaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Calcyclin on 10 µg of human lung tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)