MABS453

Anti-Axin2, clone cond4-1D5 Antibody

Name: Anti-Axin2, clone cond4-1D5 Antibody
Brand: MM

clone cond4-1D5, from rat

Synonym(s):

Axin-2, Axin-like protein, Axil, Conductin

Select a Size

All Photos(3)

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-Axin2, clone cond4-1D5 Antibody, clone cond4-1D5, from rat

biological source

rat

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

cond4-1D5, monoclonal

species reactivity

human

technique(s)

immunocytochemistry: suitable
western blot: suitable

isotype

IgG2aκ

NCBI accession no.

NP_004646

UniProt accession no.

Q9Y2T1

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... AXIN2(8313)

Analysis Note

Evaluated by Western Blotting in HCT116 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected Axin2 in 10 µg of HCT116 cell lysate.

Application

Immunocytochemistry Analysis: 20 μg/mL of this antibody from a representative lot detected Axin2 in HeLa, HEK293 and NIH-3T3 cells.
Western Blotting Analysis: A representative lot of this antibody detected Axin2 in SW 480 cell lines

Research Category
Signaling

Apoptosis & Cancer

Research Sub Category
General Post-translation Modification

This Anti-Axin2, clone cond4-1D5 Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of Axin2.

Biochem/physiol Actions

This monoclonal antibody recognizes both endogeneous and overexpressed Axin2 and does not cross-react with Axin1

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Axin-2, or Axis inhibition protein 2, is an inhibitor of the Wnt signaling pathway that down-regulates beta-catenin and APC through phosphorylation. Axin-2 abnormalities are linked to defective mismatch repair and have been found to be involved in colorectal cancer (CRC) and oligodontia-colorectal cancer syndrome (ODCRCS). Axin-2 can be found in brain and lymphoblast tissues.

~ 95 kDa observed

Immunogen

Linear peptide corresponding to Human Axin 2.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Format: Purified

Protein G Purified

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Not finding the right product?

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c