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Merck

MABT176

Anti-SOX-6, clone 3F4.1 Antibody

clone 3F4.1, from mouse

Synonym(s):

Transcription factor SOX-6

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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Product Name

Anti-SOX-6, clone 3F4.1 Antibody, clone 3F4.1, from mouse

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

3F4.1, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_001139283

UniProt accession no.

P35712

shipped in

wet ice

Gene Information

human ... SOX6(55553)

Analysis Note

Evaluated by Western Blotting in Hek-293 nuclear extract.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected SOX-6 in 10 µg of Hek-293 nuclear extract.

Application

Detect SOX-6 using this Anti-SOX-6 antibody, clone 3F4.1 validated for use in western blotting.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The protein SOX-6 which is encoded by the gene SOX6, is a transcriptional activator that binds to the enhancer sequence in DNA of 5′AACAAT3′ that is present on genes. SOX-6 plays a key role in development for several developmental systems including neurogenesis and skeleton formation. Additionally, SOX-6 is important in cardiocyte differentiation, cartilage development, cell morphogenesis, erythrocyte development, oligodendrocyte cell fate specification, positive regulation of cartilage development, positive regulation of chondrocyte differentiation, and positive regulation of mesenchymal stem cell differentiation. The activity of SOX-6 is mediated by sumoylation. SOX-6 is localized to the nucleus. SOX-6 is expressed in a wide variety of tissues both during development and in adult life, with the most abundant expression seen in skeletal muscle.
~ 92 kDa observed. Uncharacterized band(s) may appear in some lysates.

Immunogen

GST-tagged recombinant protein corresponding to human SOX-6.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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