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About This Item
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
rat, mouse
Application:
—
Citations:
9
biological source
rabbit
Quality Segment
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
rat, mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Trpv1(193034)
General description
Anti-Capsaicin Receptor (Ab-1) (824-838), rabbit polyclonal, recognizes the ~100 kDa capsaicin receptor in mouse spinal cord extract. It is validated for WB, IF & IHC in frozen and paraffin sections.
Protein A purified rabbit polyclonal antibody. Recognizes the ~100 kDa capsaicin receptor protein.
Recognizes the ~100 kDa capsaicin receptor protein in mouse spinal cord extract.
Immunogen
a synthetic peptide (EDAEVFKDSMVPGEK) corresponding to amino acids 824-838 of rat capsaicin receptor, conjugated to KLH
Application


Frozen Sections (5 g/ml, see application references)
Immunoblotting (5-10 g/ml)
Immunofluorescence (2 g/ml)
Paraffin Sections (5 g/ml; no pre-treatment required)
Packaging
Please refer to vial label for lot-specific concentration.
Analysis Note
Positive Control
Mouse spinal cord dorsal horn
Mouse spinal cord dorsal horn
Other Notes
Caterina, M.J., et al. 1999. Nature398, 436.
Gau, A., et al. 1999. Eur. J. Neurosci.11, 946.
Michael, G.J., and Priestley, J.V. 1999. J. Neurosci.19, 1844.
Caterina, M.J., et al. 1997. Nature389, 816.
Szallasi, A. 1994. Gen. Pharmacol.25, 223.
Beven, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330.
Fields, H.L. 1987. Pain (New York: McGraw-Hill).
Gau, A., et al. 1999. Eur. J. Neurosci.11, 946.
Michael, G.J., and Priestley, J.V. 1999. J. Neurosci.19, 1844.
Caterina, M.J., et al. 1997. Nature389, 816.
Szallasi, A. 1994. Gen. Pharmacol.25, 223.
Beven, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330.
Fields, H.L. 1987. Pain (New York: McGraw-Hill).
Immunohistochemistry was performed on mouse spinal cord sections fixed in 4% paraformaldehyde. Immunohistochemical staining results correlate well with other independent reports and in situ hybridization studies. Antibody should be titrated for optimal results in individual systems.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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