Shining Light on the Unknown: Standardized Non-Targeted MS Analysis
Webinar
The universe of chemicals that exist in our world is enormous and complex. Mass spectrometry-based non-targeted analysis (NTA) aims at peeling apart the complexities of mixtures and identifying chemicals using a combination of analytical chemistry and advanced data analysis. With better, and more accessible, instrumentation like high resolution mass spectrometers, academic, industrial, and government laboratories are finding novel applications of NTA for their own work. But with broad use of NTA over a wide range of laboratories and expertise comes the need to harmonize and benchmark results to improve reproducibility and comparability.
Key learnings:
- Explore the concepts of non-targeted analysis and the array of applications that have been demonstrated across many sectors.
- Learn about the metrology of non-targeted analysis, including concepts like performance metrics for qualitative chemical identifications and traceability of measurements.
- Hear about the current activities of technical and professional organizations to establish guidance and standard methods and metrics for more reproducible non-targeted analysis.
- See how national metrology institutes, like the National Institute of Standards & Technology, can enable novel method development and improve method comparability for non-targeted analysis.
Speakers
Dr. Benjamin Place
National Institute of Standards and Technology
Research Chemist
Benjamin Place received his PhD in Analytical Chemistry from Oregon State University in 2012, then came to NIST as a National Research Council Postdoctoral Fellow, where his work focused on the broad applications of non-targeted analysis (NTA) methods. Now at NIST as a federal scientist, Ben focuses on the metrology of both targeted and non-targeted measurements, including per- and polyfluoroalkyl substances, toxic chemicals in food, and biomarkers of botanical authenticity. His primary focus is on the metrological foundations of NTA, including the need for reference materials, databases, and data tools to enable researchers and regulators to understand and compare their NTA results. His work includes the use of non-targeted analysis to characterize the chemical composition of food, dietary supplements, industrial products, and other materials. He was the founding chair of the Best Practices for Non-Targeted Analysis (BP4NTA) Working Group, where he continues to work as the chair of a technical subcommittee.
Analytical chemistry
- Solid phase extraction
Duration:1h
Language:English
Session 1:Tue, October 27, 2026 3:00 PM CEST