182730 ASB-C8Ø - CAS 216667-49-1 - Calbiochem

182730
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₂₃H₄₀N₂O₄S216667-49-1

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182730-1GM
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      Plastic ampoule 1 gm
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      182730-5GM
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          Description
          OverviewA zwitterionic detergent with an aromatic core that is shown to stabilize and solubilize integral membrane proteins by breaking aggregates. Useful for protein analysis and characterization by two-dimensional (2-D) gel electrophoresis and mass spectrometry techniques. Reported to be superior to CHAPS (Cat. No. 220201) in solubilizing both an anion-channel and a G-protein coupled receptor (GPCR).
          Catalogue Number182730
          Brand Family Calbiochem®
          SynonymsC8Ø, 4-n-Octylbenzoylamido-propyl-dimethylammonio Sulfobetaine
          References
          ReferencesHenningsen, R., et al. 2002. Proteomics 2, 1479.
          Molloy, M.P. 2000. Anal. Biochem. 280, 1.
          Santoni, V., et al. 2000. Electrophoresis 21, 3329.
          Rabilloud, T., et al. 1999. Electrophoresis 20, 3603.
          Santoni, V., et al. 1999. Electrophoresis 20, 705.
          Herbert, B. 1999. Electrophoresis 20, 660.
          Chevallet, M., et al. 1998. Electrophoresis 19, 1901.
          Product Information
          CAS number216667-49-1
          FormOff-white solid
          Hill FormulaC₂₃H₄₀N₂O₄S
          Chemical formulaC₂₃H₄₀N₂O₄S
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +2°C to +8°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          ASB-C8Ø - CAS 216667-49-1 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          ASB-C8Ø - CAS 216667-49-1 - Calbiochem Certificates of Analysis

          TitleLot Number
          182730

          References

          Reference overview
          Henningsen, R., et al. 2002. Proteomics 2, 1479.
          Molloy, M.P. 2000. Anal. Biochem. 280, 1.
          Santoni, V., et al. 2000. Electrophoresis 21, 3329.
          Rabilloud, T., et al. 1999. Electrophoresis 20, 3603.
          Santoni, V., et al. 1999. Electrophoresis 20, 705.
          Herbert, B. 1999. Electrophoresis 20, 660.
          Chevallet, M., et al. 1998. Electrophoresis 19, 1901.

          Brochure

          Title
          Biological Detergents Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision21-June-2013 JSW
          SynonymsC8Ø, 4-n-Octylbenzoylamido-propyl-dimethylammonio Sulfobetaine
          DescriptionA zwitterionic detergent (zwittergent®) containing an aromatic core that has been demonstrated to stabilize and solubilize integral membrane proteins by breaking aggregates. Useful for protein analysis and characterization by two-dimensional gel electrophoresis and mass spectrometry techniques. Reported to be superior to CHAPS (Cat. No. 220201) in solubilizing an ion-channel protein and a G-protein coupled receptor (GPCR). In combination with thiourea and urea, also reported to improve the recovery of hydrophobic proteins from Arabidopsis thaliana.
          FormOff-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number216667-49-1
          Chemical formulaC₂₃H₄₀N₂O₄S
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityH₂O (50 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
          Toxicity Irritant
          ReferencesHenningsen, R., et al. 2002. Proteomics 2, 1479.
          Molloy, M.P. 2000. Anal. Biochem. 280, 1.
          Santoni, V., et al. 2000. Electrophoresis 21, 3329.
          Rabilloud, T., et al. 1999. Electrophoresis 20, 3603.
          Santoni, V., et al. 1999. Electrophoresis 20, 705.
          Herbert, B. 1999. Electrophoresis 20, 660.
          Chevallet, M., et al. 1998. Electrophoresis 19, 1901.