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Merck

RMHE-120K

MILLIPLEX® Rat Metabolic Hormone Expanded Panel

Configurable Rat Metabolic Hormone Expanded 14-Plex Panel

Synonym(s):

Rat energy balance biomarker kit, Rat hormone multiplex assay, Rat incretin and cytokine assay, Rat insulin and appetite hormone panel, Rat metabolic panel

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503


Product Name

MILLIPLEX® Rat Metabolic Hormone Expanded Panel,

usage

 kit sufficient for 96 wells

Quality Segment

species reactivity

rat

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

standard curve range: 1.4-1,000 pg/mL
(TNFα), standard curve range: 110-80,000 pg/mL
(IL-6), standard curve range: 110-80,000 pg/mL
(Insulin), standard curve range: 2.7-2,000 pg/mL
(Glucagon), standard curve range: 27-20,000 pg/mL
(GLP-1 (active)), standard curve range: 27-20,000 pg/mL
(GLP-1 total), standard curve range: 4.1-3,000 pg/mL
(GIP (total)), standard curve range: 4.1-3,000 pg/mL
(Ghrelin (active)), standard curve range: 41-30,000 pg/mL
(Amylin (active)), standard curve range: 48-35,000 pg/mL
(Leptin), standard curve range: 6.9-5,000 pg/mL
(PYY total), standard curve range: 6.9-5,000 pg/mL
(Pancreatic Polypeptide, PP), standard curve range: 6.9-5,000 pg/mL
(Secretin), standard curve range: 69-50,000 pg/mL
(C-Peptide 2), standard curve range: 69-50,000 pg/mL
(MCP-1/CCL2)

technique(s)

multiplexing: suitable

input

serum
tissue/cellular lysate
plasma
culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

This panel includes key hormones and cytokines involved in regulating glucose metabolism, appetite, insulin signaling, and inflammatory responses. Analytes such as insulin, leptin, ghrelin, GLP-1, and glucagon play central roles in energy balance and metabolic homeostasis, while cytokines like IL-6 and TNFα provide insight into inflammation-linked metabolic dysfunction. Measuring these biomarkers supports research in obesity, diabetes, appetite regulation, and metabolic syndrome in rodent models.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 14 analytes in rat serum, plasma, or cell culture supernantants.

Analytes Included: Amylin (active), C-Peptide 2, Ghrelin (active), GIP (total), GLP-1 (active), GLP-1 (total), Glucagon, IL-6, Insulin, Leptin, MCP-1/CCL2, Pancreatic Polypeptide (PP), PYY (total), Secretin, TNFα
Note: GLP-1 (Active) and GLP-1 (Total) cannot be run together in the same assay. Protease inhibitors should be added upon collection of samples.

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Measures 15 metabolic and appetite-related biomarkers in one assay
  • Suitable for serum, plasma, and tissue lysates
  • High sensitivity and specificity for low-abundance hormones
  • Multiplex format reduces sample volume and assay time
Benefits:

  • Enables comprehensive profiling of metabolic and inflammatory pathways
  • Supports research in obesity, diabetes, and energy regulation
  • Saves time and resources compared to single-analyte assays
  • Provides reliable data for rodent model studies

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



Certificates of Analysis (COA)

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