218829 Caspase-3 Substrate IX, Fluorogenic - Calbiochem

218829
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218829-1MG
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      Plastic ampoule 1 mg
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      Description
      OverviewA non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photostable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Useful for high throughput screening applications.
      Catalogue Number218829
      Brand Family Calbiochem®
      Synonyms(Z-DEVD)₂-Rh 110
      References
      ReferencesHug, H., et al. 1999. Biochemistry 38, 13906.
      Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.
      Product Information
      ATP CompetitiveN
      FormYellow lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₂H₇₈N₁₀O₂₇
      Chemical formulaC₇₂H₇₈N₁₀O₂₇
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA highly sensitive, photostable caspase-3 fluorogenic substrate
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide Sequence(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Caspase-3 Substrate IX, Fluorogenic - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Caspase-3 Substrate IX, Fluorogenic - Calbiochem Certificates of Analysis

      TitleLot Number
      218829

      References

      Reference overview
      Hug, H., et al. 1999. Biochemistry 38, 13906.
      Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-June-2008 RFH
      Synonyms(Z-DEVD)₂-Rh 110
      DescriptionA non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photo-stable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Also reported to detect capase-3 activity in intact cells by flow cytometry. Useful for high throughput screening applications. Excitation max: ~485 nm; emission max: ~535 nm.
      FormYellow lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₇₂H₇₈N₁₀O₂₇
      Peptide Sequence(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
      Purity≥95% by HPLC
      SolubilityDMSO (1 mg/ml)
      Storage -20°C
      Protect from moisture
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHug, H., et al. 1999. Biochemistry 38, 13906.
      Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.